Download PDF by Richard Bartlett;Patricia Bartlett: Ball Pythons (Reptile Keeper's Guides)

Download PDF by Richard Bartlett;Patricia Bartlett: Ball Pythons (Reptile Keeper's Guides)

By Richard Bartlett;Patricia Bartlett

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It was shown that ZntA, P1B-type Zn transporter, plays a critical role in Zn tolerance in E. 78 Interestingly, it was reported that Zn-efflux transporters are upregulated in Mn-limited conditions, suggesting that Zn toxicity is more potent when Mn concentrations in environment are lowered. In conclusion, understanding the role of metals at the interface of host–pathogen interaction is essential for determining metal-induced pathogenicity of bacteria. As has been shown in numerous studies, activation of virulence mechanisms results from the shift in the delicate balance of environmental metal concentrations.

2013;29(6):397–405; (b) Chaturvedi KS, Henderson JP. Pathogenic adaptations to host-derived antibacterial copper. Front Cell Infect Microbiol. 2014;4:3. 45. Kim EH, Nies DH, McEvoy MM, Rensing C. Switch or funnel: how RND-type transport systems control periplasmic metal homeostasis. J Bacteriol. 2011;193 (10):2381–2387. 46. Zimmermann M, Udagedara SR, Sze CM, Ryan TM, Howlett GJ, Xiao Z, Wedd AG. PcoE-a metal sponge expressed to the periplasm of copper resistance Escherichia coli. Implication of its function role in copper resistance.

130. Imlay JA. Cellular defenses against superoxide and hydrogen peroxide. Annu Rev Biochem. 2008;77:755–776. 131. Anjem A, Varghese S, Imlay JA. Manganese import is a key element of the OxyR response to hydrogen peroxide in Escherichia coli. Mol Microbiol. 2009;72(4):844–858. 132. Anjem A, Imlay JA. Mononuclear iron enzymes are primary targets of hydrogen peroxide stress. J Biol Chem. 2012;287(19):15544–15556. 133. Imlay JA. The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium.

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